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Cat. No. Product Name Target Signaling Pathways
T12203L Necrostatin 2

Others Others
Necrostatin 2 is an effective necroptosis inhibitor. Necrostatin 2 is also a RIPK1 inhibitor. EC50 for inhibition of necroptosis in FADD-deficient Jurkat T cells treated with TNF-α is 0.05 μM.
T7504 Necrostatin 2 racemate

5-[(7-氯-1H-吲哚-3-基)甲基]-3-甲基-2,4-咪唑烷二酮,Necrostatin-2 racemate

RIP kinase Apoptosis; NF-κB
Necrostatin 2 racemate (Necrostatin-2 racemate) 是一种特异性的RIPK1抑制剂,是一种稳定型 Nec-1。
T12203 Necrostatin 2 S enantiomer

Others Others
Necrostatin 2 S enantiomer is the S enantiomer of Necrostatin 2
T9095 Necrostatin-34

2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4

RIP kinase Apoptosis; NF-κB
Necrostatin-34 (2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4) 是一种 RIPK1 激酶抑制剂,通过在激酶结构域中占据一个独特的结合口袋,将 RIPK1 激酶稳定在非活性构象中。

化合物

Necrostatin 2
Cat.No: T12203L
Synonym:
Target: Others
Necrostatin 2 racemate
Cat.No: T7504
Synonym: 5-[(7-氯-1H-吲哚-3-基)甲基]-3-甲基-2,4-咪唑烷二酮,Necrostatin-2 racemate
Target: RIP kinase
Necrostatin 2 S enantiomer
Cat.No: T12203
Synonym:
Target: Others
Necrostatin-34
Cat.No: T9095
Synonym: 2-{[3-cyano-4-(4-methylphenyl)-6-oxo-1,4
Target: RIP kinase
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